Treatment with ciclosporin This information leaflet is for patients who have been prescribed ciclosporin as part of immuno-suppressive treatment (IST) that is given with Anti-Thymocyte Globulin(ATG). What is ciclosporin? Ciclosporin is an immuno-suppressant medicine which has been used for many years to treat aplastic anaemia. It works by restricting the way your immune system reacts against your own bone marrow, suppressing or quietening down your immune system to help your bone marrow heal and recover. Purpose of the refreshed fact sheet The fact sheet explains what treatment involving ciclosporin is, how it works and any potential side effects or complications. You can download it here.