A rare bone marrow failure disease caused by low blood cell counts.
A type of therapy
An antibody based therapy that is aimed at Lymphocytes (A type of white blood cell and key part of the immune cell that attacks the stem cells in the bone marrow). This therapy is commonly used as part of the preparatory treatment before the stem cell transplant.
Amanda joined the AAT's Board of Trustees in April 2020 and became our chair in October the same year.
Amanda is an executive coach, working with leaders and managers, mainly in the arts, education and the third sector. Previously she had been editorial director at Heinemann publisher and MD of the literary estate of Roald Dahl. While there she developed and had responsibility for two charities, Roald Dahl’s Marvellous Children’s Charity, a grant-making foundation working to improve the lives of seriously ill children, and the Museum and Story Centre which bears the author’s name, of which she became chair. Amanda’s commitment to our work is founded on the experience of her daughter, who was diagnosed with Aplastic Anaemia in 2019. She is also a volunteer prison representative for the Shannon Trust, which aims to transform peoples’ lives by encouraging prisoners who can read to teach literacy skills to those who cannot.
A number of drugs that can be used to help fight/stop fungal infections. Examples of these drugs are amphotericin, posaconazole, fluconazole, voriconazole and nystatin.
Wondering how to best support someone close to you who has received a diagnosis? Daniel shares what he found most useful when he was going through the early stages of aplastic anaemia.
Further information you might find useful...
Need more support? Contact our support team.
Daniel gives his tips on what to pack for your time in isolation.
Daniel tells the story of his bone marrow transplant experience - how he felt before and afterwards, and the things that surprised him along the way!
Further information you might find useful...
Daniel has received a question from Fadi about her brother who is likely to receive a bone marrow transplant.
ATG is a purified serum that suppresses the immune system to allow the bone marrow time to recover. It is produced by injecting animals (horse or rabbit) with white blood cells called lymphocytes. The animal then makes antibodies which are collected and purified to produce globulin.
ATG can either be used ahead of a stem cell transplant (rabbit) or with ciclosporin as a stand-alone treatment to let the bone marrow recover.
Atif joined The AAT in February 2021 on secondment from Maggie’s for six months.
He has over 15 years experience of providing welfare benefits advice. He is keen to establish a service for Aplastic Anaemia (AA) patients to meet the unmet need. The extra costs an AA diagnosis brings can be overwhelming for some. The welfare benefits system is designed to meet the needs of AA patients in these difficult times.
Not all benefits are income related; some depend on national insurance contributions and some on how the illness is affecting someone in their day-to-day activities. In addition Atif can also advise about claiming travel costs to hospital for NHS treatment.
Atif lives in Oxford. He loves to play table tennis and is a registered Table Tennis England level 2 coach. He is passionate about coaching children, teenagers as well as young adults who have successfully gone on to win local tournaments.
He would be keen to hear from you to advise you on your benefits entitlement. He usually works on a Monday. He can be contacted on [email protected], or you can book a free benefits consultation here.
A small sample of bone marrow taken for examination
A small bit of bone marrow that is taken under local anaesthetic from either the hip bone or breast bone. The sample is then examined by microscope for abnormalities in the young blood cells.
Bone marrow biopsy and trephine sample
A small section of bone is taken under anaesthetic from either the hip or breast bones for examination. This is usually performed at the same time as the aspirate is taken.
A temporary thin tube
A temporary thin tube put into the vein for the giving of fluids or intravenous drugs, or for taking of blood samples.
A central catheter/line
A central venous catheter, more commonly called a central line or HICKMAN line is a small flexible plastic tube put into the large vein somewhere above the heart. This is used for giving fluids/drugs or for taking blood samples.
An immunosuppressant drug
Is an immunosuppressant drug which can be used for the treatment of aplastic anaemia.
Umbilical cord blood
Blood from the umbilical cord taken at the time of birth. This source of blood is very high in stem cells and can be used as a stem cell source for a stem cell transplant.
A reduction in the number of mature blood cells
There are several types of cytopenia depending on what type of blood cells are depleted:
Dagmara joined the AAT in 2018 to build a Trusts & Foundations income stream. In 2020 her role evolved to include impact management.
Typically, Dagmara’s work involves gathering evidence of need to support future projects and initiatives of the charity, developing compelling cases for support, researching funding opportunities and partnerships, putting strong grant applications, nourishing relationships and connections that matter, using best practice in monitoring and evaluation to plan and measure the impact of the AAT’s work.
Before joining the AAT, for many years Dagmara has worked in business development roles for consulting companies in the UK and abroad specialised in technology, innovation and international development.
In the AAT, Dagmara discovered the beauty of working in a small team that delivers work that no other organization in the UK does. She loves learning about patients’ needs and building funding propositions that address them.
A type of curative therapy
Treatment with the potential of restoring the bone marrow function so that patients can become transfusion-free, at less risk of infection/bleeding and live a more normal lifestyle.
Anita is a Consultant in Clinical Haematology, Lead Consultant for National PNH Service in England, St James Hospital, Leeds
Dominic is a a Consultant Haematologist, Honorary Senior Lecturer at Aberdeen Royal Infirmary and The University of Aberdeen
Keith is a Senior Lecturer, Honorary and Consultant Haematologist, Clinical Lead for Blood and Bone Marrow Transplantation, at the Cardiff and Vale University Health Board